Erythrapheresis in polycythemia.

Relative Polycythemia—The Polycythemia of Stress *

In a group of normal subjects going from sea level to approximately 16,000 feet we observed that very soon after arrival at high altitude there was hemoconcentration, as indicated by an increased red cell count and hematocrit, but a normal total red cell volume and a low plasma volume. This "apparent increase" in the number of red blood cells in the early days after arrival at high altitude is,...

Congenital polycythemia in Chuvashia.

Familial and congenital polycythemia, not due to high oxygen affinity hemoglobin or reduced 2,3-diphosphoglycerate in erythrocytes, is common in the Chuvash population of the Russian Federation. Hundreds of individuals appear to be affected in an autosomal recessive pattern. We studied six polycythemic Chuvash patients <20 years of age from unrelated families and 12 first-degree family members....

Muramidase in polycythemia vera.

Radiophosphorous Therapy in Polycythemia.

By BARUCH MODAN I HE USE of pa2 in the therapy of polycythemia vera has continued to be a controversial subject since it was first introduced.15”5 Although considered as the ultimate treatment for polycythemia vera by many hematologists it has, on the other hand, been discredited by others as being responsible for a high proportion of deaths from acute leukemia. The main obstacle to an objectiv...

Imatinib mesylate in polycythemia vera

In the September 15, 2003, issue of Blood,1 Oehler et al describe imatinib mesylate inhibition of the autonomous in vitro proliferation of peripheral blood– and bone marrow–derived polycythemia vera (PV) erythroid burst-forming units (BFU-Es). While their results superficially correlate with the previously published in vivo clinical observations of Silver,2 the conclusions of Oehler et al are a...